ࡱ > R bjbj 8 * + + + 8 c + 3 c c c !3 #3 #3 #3 #3 #3 #3 $ 6 8 . G3 i c c c c c G3 H 3 u- u- u- c !3 u- c !3 u- u- u- Jf + ) u- 3 3 0 3 u- 8 )- L 8 u- u- 8 - c c u- c c c c c G3 G3 u- c c c 3 c c c c 8 c c c c c c c c c : @nL p - P L A 2 0o x - L D L NQ_u`R |7hlxSuS z^sQ|vxvz 0Xd0vv cvz@nˆ}vvsQxvL p - P L A 2 0'lSNO[^ˆ}vo x - L D L NQ_u`R |7hlxSuS z^vsQ|0el [2 8 ON3z[W_~u`A ~ 3 2 O3z[W_~u`B ~ NS3 2 OeP^SOhC ~ R+RۏLL p - P L A 2 0o x - L D L 4ls^hKm RgQ_u`uS z^NvQvvsQ'`0~g N~L p - P L A 2 0o x - L D L 4ls^[k ]_GWwQ g~f[aIN( P < 0 . 0 5 ) A ~0B ~L p - P L A 2 0o x - L D L 4ls^GW>fWؚNC ~ A ~L p - P L A 2 0o x - L D L 4ls^0G e n s i n i yR>fWؚNB ~( P < 0 . 0 5 ) P e r s o n vsQRg>f:y Q_u`vG e n s i n i yRGWN@nL p - P L A 2 0o x - L D L 4ls^HT>fWckvsQP < 0 . 0 5 YCQVR_Rg>f:y Q_u`@nL p - P L A 2 0o x - L D L 4ls^[G e n s i n i yRvSS GWwQ g>fWvq_TP < 0 . 0 5 0~ Q_u`vR |7hlxSuS z^N@nL p - P L A 2 0o x - L D L 4ls^ gsQ uS z^%N͑ RL p - P L A 2 0o x - L D L 4ls^ؚ0 0sQ.͋0@nˆ}vvsQxv'lSNO[^ˆ}vQ_uR |7hlxSuS z^ T h e C o r r e l a t i o n R e s e a r c h b e t w e e n t h e L e v e l s o f S e r u m L i p o p r o t e i n A s s o c i a t e d P h o s p h o l i p a s e A 2 a n d O x i d i z e d L D L a n d S e v e r i t y o f A t h e r o s c l e r o s i s i n P a t i e n t s w i t h C o r o n a r y H e a r t D i s e a s e 0A b s t r a c t 0O b j e c t i v e T o i n v e s t i g a t e t h e correlation between the levels of serum lipoprotein associated phospholipase A2 (Lp-PLA2)and Oxidized LDL (ox-LDL)and severity of atherosclerosis in patients with coronary heart disease.Methods The levels of Lp-PLA2 and ox-LDL in 28 cases of patients with unstable angina pectoris (group A), 32 cases of patients with Stable angina pectoris(group B) and 32 cases of healthy subject(group C) were measured respectively. Results The differences of levels of Lp-PLA2 and ox-LDL in three groups were statistically significant (P<0.05). The levels of Lp-PLA2 and ox-LDL in group A and group B were all significantly higher than those of group C and the Gensini score, levels of Lp-PLA2 and ox-LDL in group A were all significantly higher than those of group B(P<0.05).After Person correlation analysis, the levels of Lp-PLA2 and ox-LDL of patients with CHD were positively related with Gensini score(P<0.05). Multiple regression analysis showed that, the Gensini score of patients with CHD was effected significantly by the leve l s o f L p - P L A 2 a n d o x - L D L ( P < 0 . 0 5 ) . C o n c l u s i o n T h e s e v e r i t y o f a t h e r o s c l e r o s i s i n p a t i e n t s w i t h C H D i s r e l a t e d w i t h t h e l e v e l s o f L p - P L A 2 a n d o x - L D L , t h e m o r e s e r i o u s i n a t h e r o s c l e r o s i s , t h e h i g h e r i n t h e l e v e l s o f L p - P L A 2 a n d o x - L D L . 0K e y w o r d s 0s e r u m l i p o p r o t e i n a s s o c i a t e d p h o s p h o l i p a s e A 2 ; O x i d i z e d L D L ; c o r o n a r y h e a r t d i s e a s e ; a t h e r o s c l e r o s i s ; s e v e r i t y Q_uc o r o n a r y h e a r t d i s e a s e , C H D /f Ny8^v_@{uuKN N @wR {X_8^0@{T)\0@\gZƖNS@hQv_c$OS^I{YyV }v\O(u \[f[`N u_~uur[ 1 ] (W4N^
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